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Notícias

21/09/2021

COVID-19 and the cardiovascular system: insights into effects and treatments

Coronavirus disease 2019 (COVID-19), an acute and highly transmissible infectious disease, has reached a pandemic level since 11 March 2020...

Repositório Covid-19
21/09/2021

New Insights Into Drug Repurposing for COVID-19 Using Deep Learning

The coronavirus disease 2019 (COVID-19) has continued to spread worldwide since late 2019. To expedite the process of providing treatment...

Repositório Covid-19
21/09/2021

Synthesis and antiviral activity of fatty acyl conjugates of remdesivir against severe acute respiratory syndrome coronavirus 2 and Ebola virus

We report here the synthesis, purification, and characterization of mono- and di-fatty acyl conjugates of remdesivir (RDV) and their in ...

Repositório Covid-19
21/09/2021

REGEN-COV Antibody Combination and Outcomes in Outpatients with Covid-19

In the phase 1–2 portion of an adaptive trial, REGEN-COV, a combination of the monoclonal antibodies casirivimab and imdevimab, reduced...

Repositório Covid-19
20/09/2021

Safety and immunogenicity of an inactivated COVID-19 vaccine, BBIBP-CorV, in people younger than 18 years: a randomised, double-blind, controlled, phase 1/2 trial

Although SARS-CoV-2 infection often causes milder symptoms in children and adolescents, young people might still play a key part in...

Repositório Covid-19
20/09/2021

Multi-level inhibition of coronavirus replication by chemical ER stress

Coronaviruses (CoVs) are important human pathogens for which no specific treatment is available. Here, we provide evidence that pharmacological reprogramming...

Repositório Covid-19
20/09/2021

The critical role of mesenchymal stromal/stem cell therapy in COVID-19 patients: An updated review

New coronavirus disease 2019 (COVID-19), as a pandemic disaster, has drawn the attention of researchers in various fields to discover...

Repositório Covid-19
Serviço exclusivo para associados à ABIFINA
17/09/2021

Serviço exclusivo para associados à ABIFINA

O número de pedidos de patentes monitoradas pela ABIFINA ultrapassou a marca de
3 mil. Agora, são 730 patentes...

Acontece na ABIFINA
16/09/2021

Novel ACE2 protein interactions relevant to COVID-19 predicted by evolutionary rate correlations

Angiotensin-converting enzyme 2 (ACE2) is the cell receptor that the coronavirus SARS-CoV-2 binds to and uses to enter and infect...

Repositório Covid-19
16/09/2021

Immune and cellular damage biomarkers to predict COVID-19 mortality in hospitalized patients

Early prediction of COVID-19 in-hospital mortality relies usually on patients’ preexisting comorbidities and is rarely reproducible in independent cohorts. We...

Repositório Covid-19
16/09/2021

Assessment of the binding interactions of SARS-CoV-2 spike glycoprotein variants

Severe acute respiratory syndrome-associated coronavirus 2 is a major global health issue and is driving the need for new therapeutics....

Repositório Covid-19
16/09/2021

Anti-SARS-CoV-2 IgG and IgA antibodies in COVID-19 convalescent plasma do not facilitate antibody-dependent enhance of viral infection

The novel coronavirus SARS-CoV2, which causes COVID-19, has resulted in the death of nearly 4 million people within the last...

Repositório Covid-19
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