Notícias

Abstract

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has recently emerged throughout the world,...

Abstract

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) helicase NSP13 plays a conserved role in the replication of coronaviruses and...

Abstract

Objectives

Severe COVID-19 is associated with immune dysregulation and hyperinflammation (lymphocyte exhaustion and elevated interleukin 6. Pembrolizumab (P; immune-activating...

Abstract

SARS-CoV-2, the newly emerged virus of the Coronaviridae family is causing havoc worldwide. The novel coronavirus 2019 was first...

Abstract

Description:

Coronavirus disease 2019 convalescent plasma (CCP) has emerged as a potential treatment of COVID-19. However, meta-analysis data and...

O Instituto de Tecnologia em Fármacos – Farmanguinhos/Fiocruz, tendo em vista a previsão do item 4.3 da Chamada Pública  nº...

O Instituto de Tecnologia em Fármacos – Farmanguinhos/Fiocruz, tendo em vista a previsão do item 4.3 da Chamada Pública  nº...

Summary

Background

We assessed the efficacy of a receptor-binding domain (RBD)-based protein subunit COVID-19 vaccine.

Abstract

The worldwide COVID-19 pandemic caused by the coronavirus SARS-CoV-2 urgently demands novel direct antiviral treatments. The main protease (Mpro)...

Abstract

The ongoing COVID-19 pandemic has claimed more than 6 million lives and continues to test the world economy and...

Abstract

Since December 2019, the coronavirus (COVID-19) pandemic has imposed huge burdens to the whole world, seriously affecting global economic...

Abstract

Several studies have shown that interleukin 6 (IL-6) is a multifunctional cytokine with both pro-inflammatory and anti-inflammatory activity, depending...