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Notícias

04/12/2021

Understanding the clinical utility of favipiravir (T-705) in coronavirus disease of 2019: a review

The coronavirus disease of 2019 (COVID-19) has caused significant morbidity and mortality among infected individuals across the world. High transmissibility...

Repositório Covid-19
Prati-Donaduzzi investirá em novos medicamentos e produtos para o tratamento de doenças do Sistema Nervoso Central
03/12/2021

Prati-Donaduzzi investirá em novos medicamentos e produtos para o tratamento de doenças do Sistema Nervoso Central

Empresa completa 28 anos e prevê diversificação e ampliação do portfólio. A ambição da farmacêutica é se tornar num curto...

Associado em foco
03/12/2021

Drug repurposing strategies and key challenges for COVID-19 management

COVID-19 is a clinical outcome of viral infection emerged due to strain of beta coronavirus which attacks the type-2 pneumocytes...

Repositório Covid-19
03/12/2021

Study of immune-mediated mechanisms in patients tested positive for SARS-CoV-2: phenotypic and functional analysis of monocytes, NK and T cells in the blood of subjects affected by COVID 19

The novel coronavirus has a high mortality rate (over 1% for patients older than 50). This could be only partially...

Repositório Covid-19
03/12/2021

In-silico screening of naturally derived phytochemicals against SARS-CoV Main protease

Coronavirus disease 2019 (COVID-19) is a rapidly growing pandemic that requires urgent therapeutic intervention. Finding potential anti COVID-19 drugs aside...

Repositório Covid-19
03/12/2021

Spherical Neutralizing Aptamer Inhibits SARS-CoV-2 Infection and Suppresses Mutational Escape

New neutralizing agents against SARS-CoV-2 and associated mutant strains are urgently needed for the treatment and prophylaxis of COVID-19. Herein,...

Repositório Covid-19
03/12/2021

A randomised controlled trial testing the efficacy of Fit after COVID, a cognitive behavioural therapy targeting severe post-infectious fatigue following COVID-19 (ReCOVer): study protocol

Coronavirus disease 2019 (COVID-19) results in debilitating long-term symptoms, often referred to as Post-Acute Sequelae of SARS-CoV-2 Infection (PASC), in...

Repositório Covid-19
02/12/2021

Covid-19 Vaccine Effectiveness in New York State

Population-based data from the United States on the effectiveness of the three coronavirus disease 2019 (Covid-19) vaccines currently authorized by...

Repositório Covid-19
02/12/2021

Comparative Effectiveness of BNT162b2 and mRNA-1273 Vaccines in U.S. Veterans

The messenger RNA (mRNA)–based vaccines BNT162b2 and mRNA-1273 are more than 90% effective against coronavirus disease 2019 (Covid-19). However, their...

Repositório Covid-19
02/12/2021

Amantadine inhibits known and novel ion channels encoded by SARS-CoV-2 in vitro

The dire need for COVID-19 treatments has inspired strategies of repurposing approved drugs. Amantadine has been suggested as a candidate,...

Repositório Covid-19
02/12/2021

Immune-mediated neurological syndrome in SARS-CoV-2 infection: a review of literature on autoimmune encephalitis in COVID-19

The novel Coronavirus Disease 2019 (COVID-19) is an infection caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) which...

Repositório Covid-19
02/12/2021

Discovery of 9,10-dihydrophenanthrene derivatives as SARS-CoV-2 3CLpro inhibitors for treating COVID-19

The epidemic coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has now spread worldwide and...

Repositório Covid-19
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