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CONTATO

Repositório Covid-19

09/08/2022

Seasonal variation of the composition of essential oils from Piper cernuum Vell and Piper rivinoides Kunth, ADMET study, DFT calculations, molecular docking and dynamics studies of major components as potent inhibitors of the heterodimer methyltransferase complex NSP16-NSP10 SARS COV-2 protein

Abstract

09/08/2022

Selective serotonin reuptake inhibitor (SSRI) antidepressants reduce COVID-19 infection: prospects for use

Abstract

Purpose

The absence of specific treatments for COVID-19 leads to an intense global effort in the search for new...

09/08/2022

A Multiscale Model of COVID-19 Dynamics

Abstract

COVID-19, caused by the infection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been a global pandemic and...

09/08/2022

Schaftoside inhibits 3CLpro and PLpro of SARS-CoV-2 virus and regulates immune response and inflammation of host cells for the treatment of COVID-19

Abstract

It is an urgent demand worldwide to control the coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute...

09/08/2022

Immunogenicity of ChAdOx1-nCoV-19 vaccine in solid malignancy patients by treatment regimen versus healthy controls: A prospective, multicenter observational study

Summary

Background

Limited data exists regarding the efficacy of ChAdOx1-nCoV-19 vaccine against Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) in...

08/08/2022

Vaccine effectiveness of two-dose BNT162b2 against symptomatic and severe COVID-19 among adolescents in Brazil and Scotland over time: a test-negative case-control study

Summary

Background

Little is known about vaccine effectiveness over time among adolescents, especially against the SARS-CoV-2 omicron (B.1.1.529) variant. This...

04/08/2022

Multivalent ACE2 engineering—A promising pathway for advanced coronavirus nanomedicine development

Abstract

The spread of coronavirus diseases has resulted in a clarion call to develop potent drugs and vaccines even as...

04/08/2022

Direct capture of neutralized RBD enables rapid point-of-care assessment of SARS-CoV-2 neutralizing antibody titer

Summary

Neutralizing antibody (NAb) titer is a key biomarker of protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection,...

03/08/2022

Scope of repurposed drugs against the potential targets of the latest variants of SARS-CoV-2

Abstract

The unprecedented outbreak of the severe acute respiratory syndrome (SARS) Coronavirus-2, across the globe, triggered a worldwide uproar in...

02/08/2022

Allosteric Binding Sites of the SARS-CoV-2 Main Protease: Potential Targets for Broad-Spectrum Anti-Coronavirus Agents

Lara Alzyoud,1 Mohammad A Ghattas,1,2 Noor Atatreh1,2

29/07/2022

Omicron SARS-CoV-2 epidemic in England during February 2022: A series of cross-sectional community surveys

Summary

Background

The Omicron wave of COVID-19 in England peaked in January 2022 resulting from the rapid transmission of the...

29/07/2022

Human antibodies to SARS-CoV-2 with a recurring YYDRxG motif retain binding and neutralization to variants of concern including Omicron

Abstract

Studying the antibody response to SARS-CoV-2 informs on how the human immune system can respond to antigenic variants as...

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