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CONTATO

Repositório Covid-19

27/07/2022

Differential neutralization and inhibition of SARS-CoV-2 variants by antibodies elicited by COVID-19 mRNA vaccines

Abstract

The evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in the emergence of new variant lineages...

27/07/2022

A live-attenuated SARS-CoV-2 vaccine candidate with accessory protein deletions

Abstract

We report a live-attenuated SARS-CoV-2 vaccine candidate with (i) re-engineered viral transcription regulator sequences and (ii) deleted open-reading-frames (ORF)...

22/07/2022

Neutralising antibody responses to SARS-CoV-2 omicron among elderly nursing home residents following a booster dose of BNT162b2 vaccine: A community-based, prospective, longitudinal cohort study

Summary

Background

The protective immunity against omicron following a BNT162b2 Pfizer booster dose among elderly individuals (ie, those aged >65...

22/07/2022

Safety and immunogenicity of a SARS-CoV-2 recombinant protein nanoparticle vaccine (GBP510) adjuvanted with AS03: A randomised, placebo-controlled, observer-blinded phase 1/2 trial

Summary

Background

Vaccination has helped to mitigate the COVID-19 pandemic. Ten traditional and novel vaccines have been listed by the...

21/07/2022

BNT162b2 Vaccine Effectiveness against Omicron in Children 5 to 11 Years of Age

Abstract

BACKGROUND

Limited evidence is available on the real-world effectiveness of the BNT162b2 vaccine against coronavirus disease 2019 (Covid-19) and...

20/07/2022

Effectiveness of BNT162b2 Vaccine against Omicron in Children 5 to 11 Years of Age

Abstract

BACKGROUND

Since it was first identified in early November 2021, the B.1.1.529 (omicron) variant of severe acute respiratory syndrome...

12/07/2022

Post-recovery COVID-19 and incident heart failure in the National COVID Cohort Collaborative (N3C) study

Abstract

Cardiac involvement has been noted in COVID-19 infection. However, the relationship between post-recovery COVID-19 and development of de novo...

11/07/2022

Limited neutralisation of the SARS-CoV-2 Omicron subvariants BA.1 and BA.2 by convalescent and vaccine serum and monoclonal antibodies

Summary

Background

In recent months, Omicron variants of SARS-CoV-2 have become dominant in many regions of the world, and case...

11/07/2022

SARS-CoV-2 accelerated clearance using a novel nitric oxide nasal spray (NONS) treatment: A randomized trial

Summary

Background

Additional outpatient therapies which are readily accessible will be essential to reduce COVID-19 illness progression in high risk...

09/07/2022

Safety and efficacy of mesenchymal stem cells in severe/critical patients with COVID-19: A systematic review and meta-analysis

Summary

Background

The present study aims to better understand the efficacy and safety of mesenchymal stromal cells (MSCs) in treating...

08/07/2022

Robust long-term immunity to SARS-CoV-2 in patients recovered from severe COVID-19 after interleukin-6 blockade

Summary

Background

Whether interleukin-6 (IL-6) blockade in patients with COVID-19 will affect the protective immunity against SARS-CoV-2 has become an...

07/07/2022

Effects of Previous Infection and Vaccination on Symptomatic Omicron Infections

Abstract

BACKGROUND

The protection conferred by natural immunity, vaccination, and both against symptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)...

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