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Repositório Covid-19

09/09/2021

Vaccination reduces need for emergency care in breakthrough COVID-19 infections: A multicenter cohort study

While recent literature has shown the efficacy of the SARS-CoV-2 vaccine in preventing infection, it’s impact on need for emergency...

08/09/2021

Effectiveness of Covid-19 Vaccines in Ambulatory and Inpatient Care Settings

There are limited data on the effectiveness of the vaccines against symptomatic coronavirus disease 2019 (Covid-19) currently authorized in the...

08/09/2021

EFFECT OF TOCILIZUMAB IN MORTALITY AMONG PATIENTS WITH SEVERE AND CRITICAL COVID-19: EXPERIENCE IN A THIRD-LEVEL MEDICAL CENTER

The lack of effective treatment options to reduce COVID-19 associated mortality, disease progression, and the need for invasive mechanical ventilation...

02/09/2021

Discovery of novel inhibitors of SARS-CoV-2 main protease

Corona Virus Disease 2019 (COVID-19), referred to as ‘New Coronary Pneumonia’, is a type of acute infectious disease caused by...

01/09/2021

Are laboratory-made, COVID-19-specific monoclonal antibodies an effective treatment for COVID-19?

Antibodies are made by the body as a defence against disease. However, they can also be produced in a laboratory...

01/09/2021

Pseudoephedrine and its derivatives antagonize wild and mutated severe acute respiratory syndrome-CoV-2 viruses through blocking virus invasion and antiinflammatory effect

The coronavirus disease 2019 has infected over 150 million people worldwide and led to over 3 million deaths. Severe acute...

01/09/2021

In-silico strategies to combat COVID-19: A comprehensive review

The novel coronavirus SARS-CoV-2 since its emergence at Wuhan, China in December 2019 has been creating global health turmoil despite...

30/08/2021

Utility of various inflammatory markers in predicting outcomes of hospitalized patients with COVID-19 pneumonia

The aim of the study is to study the utility of various inflammatory markers in predicting outcomes of hospitalized patients...

30/08/2021

Metoprolol in Critically Ill Patients With COVID-19

Severe coronavirus disease-2019 (COVID-19) can progress to an acute respiratory distress syndrome (ARDS), which involves alveolar infiltration by activated neutrophils....

30/08/2021

GalNAc-siRNA conjugates: Prospective tools on the frontier of anti-viral therapeutics

The growing use of short-interfering RNA (siRNA)-based therapeutics for viral diseases reflects the most recent innovations in anti-viral vaccines and...

30/08/2021

Development of Effective Therapeutic Molecule from Natural Sources against Coronavirus Protease

The SARS-CoV-2 main protease (Mpro) is one of the molecular targets for drug design. Effective vaccines have been identified as...

28/08/2021

The rapid adaptation of SARS-CoV-2–rise of the variants: transmission and resistance

The causative factor of COVID-19, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is continuously mutating. Interestingly, identified mutations mainly occur...

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