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Repositório Covid-19

25/09/2021

Titers of SARS CoV-2 antibodies in cord blood of neonates whose mothers contracted SARS CoV-2 (COVID-19) during pregnancy and in those whose mothers were vaccinated with mRNA to SARS CoV-2 during pregnancy

We compared neonatal immunity after vaccination against SARS-CoV-2 during pregnancy to that achieved after maternal infection.

23/09/2021

SARS-CoV-2 mucosal antibody development and persistence and their relation to viral load and COVID-19 symptoms

Although serological studies have shown that antibodies against SARS-CoV-2 play an important role in protection against (re)infection, the dynamics of...

22/09/2021

Infections, hospitalisations, and deaths averted via a nationwide vaccination campaign using the Pfizer–BioNTech BNT162b2 mRNA COVID-19 vaccine in Israel: a retrospective surveillance study

On Dec 20, 2020, Israel initiated a nationwide COVID-19 vaccination campaign for people aged 16 years and older and exclusively...

22/09/2021

Efficacy of the mRNA-1273 SARS-CoV-2 Vaccine at Completion of Blinded Phase

At interim analysis in a phase 3, observer-blinded, placebo-controlled clinical trial, the mRNA-1273 vaccine showed 94.1% efficacy in preventing coronavirus...

22/09/2021

Remdesivir use and outcomes during the FDA COVID-19 emergency use authorization period

Remdesivir (RDV) was approved for treatment of coronavirus disease 2019 (COVID-19), in May 2020 under US Food and Drug Administration...

22/09/2021

No significant benefit of moderate-dose vitamin C on severe COVID-19 cases

There is no specific drug for coronavirus disease 2019 (COVID-19). We aimed to investigate the possible clinical efficacy of moderate-dose...

21/09/2021

Low-dose radiation therapy for COVID-19 pneumonia: a pilot study

The World Health Organization (WHO) has declared coronavirus disease 2019 (COVID-19) as pandemic in March 2020. Currently there is no...

21/09/2021

COVID-19 and the cardiovascular system: insights into effects and treatments

Coronavirus disease 2019 (COVID-19), an acute and highly transmissible infectious disease, has reached a pandemic level since 11 March 2020...

21/09/2021

New Insights Into Drug Repurposing for COVID-19 Using Deep Learning

The coronavirus disease 2019 (COVID-19) has continued to spread worldwide since late 2019. To expedite the process of providing treatment...

21/09/2021

Synthesis and antiviral activity of fatty acyl conjugates of remdesivir against severe acute respiratory syndrome coronavirus 2 and Ebola virus

We report here the synthesis, purification, and characterization of mono- and di-fatty acyl conjugates of remdesivir (RDV) and their in ...

21/09/2021

REGEN-COV Antibody Combination and Outcomes in Outpatients with Covid-19

In the phase 1–2 portion of an adaptive trial, REGEN-COV, a combination of the monoclonal antibodies casirivimab and imdevimab, reduced...

20/09/2021

Safety and immunogenicity of an inactivated COVID-19 vaccine, BBIBP-CorV, in people younger than 18 years: a randomised, double-blind, controlled, phase 1/2 trial

Although SARS-CoV-2 infection often causes milder symptoms in children and adolescents, young people might still play a key part in...

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