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Notícias

06/12/2021

Immunogenicity, safety, and reactogenicity of heterologous COVID-19 primary vaccination incorporating mRNA, viral-vector, and protein-adjuvant vaccines in the UK (Com-COV2): a single-blind, randomised, phase 2, non-inferiority trial

Given the importance of flexible use of different COVID-19 vaccines within the same schedule to facilitate rapid deployment, we studied...

Repositório Covid-19
06/12/2021

Câmara de Comércio Exterior atualiza Nomenclatura Comum do Mercosul

O Comitê-Executivo de Gestão da Câmara de Comércio Exterior (Gecex/Camex) aprovou na última segunda-feira (29/11) a Resolução Gecex nº 272,...

Acontece na ABIFINA
05/12/2021

Computational Simulation of HIV Protease Inhibitors to the Main Protease (Mpro) of SARS-CoV-2: Implications for COVID-19 Drugs Design

SARS-CoV-2 is highly homologous to SARS-CoV. To date, the main protease (Mpro) of SARS-CoV-2 is regarded as an important drug...

Repositório Covid-19
04/12/2021

Understanding the clinical utility of favipiravir (T-705) in coronavirus disease of 2019: a review

The coronavirus disease of 2019 (COVID-19) has caused significant morbidity and mortality among infected individuals across the world. High transmissibility...

Repositório Covid-19
Prati-Donaduzzi investirá em novos medicamentos e produtos para o tratamento de doenças do Sistema Nervoso Central
03/12/2021

Prati-Donaduzzi investirá em novos medicamentos e produtos para o tratamento de doenças do Sistema Nervoso Central

Empresa completa 28 anos e prevê diversificação e ampliação do portfólio. A ambição da farmacêutica é se tornar num curto...

Associado em foco
03/12/2021

Drug repurposing strategies and key challenges for COVID-19 management

COVID-19 is a clinical outcome of viral infection emerged due to strain of beta coronavirus which attacks the type-2 pneumocytes...

Repositório Covid-19
03/12/2021

Study of immune-mediated mechanisms in patients tested positive for SARS-CoV-2: phenotypic and functional analysis of monocytes, NK and T cells in the blood of subjects affected by COVID 19

The novel coronavirus has a high mortality rate (over 1% for patients older than 50). This could be only partially...

Repositório Covid-19
03/12/2021

In-silico screening of naturally derived phytochemicals against SARS-CoV Main protease

Coronavirus disease 2019 (COVID-19) is a rapidly growing pandemic that requires urgent therapeutic intervention. Finding potential anti COVID-19 drugs aside...

Repositório Covid-19
03/12/2021

Spherical Neutralizing Aptamer Inhibits SARS-CoV-2 Infection and Suppresses Mutational Escape

New neutralizing agents against SARS-CoV-2 and associated mutant strains are urgently needed for the treatment and prophylaxis of COVID-19. Herein,...

Repositório Covid-19
03/12/2021

A randomised controlled trial testing the efficacy of Fit after COVID, a cognitive behavioural therapy targeting severe post-infectious fatigue following COVID-19 (ReCOVer): study protocol

Coronavirus disease 2019 (COVID-19) results in debilitating long-term symptoms, often referred to as Post-Acute Sequelae of SARS-CoV-2 Infection (PASC), in...

Repositório Covid-19
02/12/2021

Covid-19 Vaccine Effectiveness in New York State

Population-based data from the United States on the effectiveness of the three coronavirus disease 2019 (Covid-19) vaccines currently authorized by...

Repositório Covid-19
02/12/2021

Amantadine inhibits known and novel ion channels encoded by SARS-CoV-2 in vitro

The dire need for COVID-19 treatments has inspired strategies of repurposing approved drugs. Amantadine has been suggested as a candidate,...

Repositório Covid-19
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