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Notícias

02/04/2022

Efficacy, safety, and immunogenicity of the DNA SARS-CoV-2 vaccine (ZyCoV-D): the interim efficacy results of a phase 3, randomised, double-blind, placebo-controlled study in India

ZyCoV-D, a DNA-based vaccine, showed promising safety and immunogenicity in a phase 1/2 trial. We now report the interim efficacy...

Repositório Covid-19
02/04/2022

Multifaceted roles of plant derived small molecule inhibitors on replication cycle of SARS-CoV-2

Coronavirus disease 2019 (COVID-19) is an illness caused by the new coronavirus severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2)....

Repositório Covid-19
02/04/2022

Dichlorophenylpyridine-Based Molecules Inhibit Furin through an Induced-Fit Mechanism

Inhibitors of the proprotein convertase furin might serve as broad-spectrum antiviral therapeutics. High cellular potency and antiviral activity against acute...

Repositório Covid-19
01/04/2022

Induction of SARS-CoV-2 neutralizing antibodies by CoronaVac and BNT162b2 vaccines in naïve and previously infected individuals

A major challenge of the SARS-CoV-2 pandemic is to better define “protective thresholds” to guide the global response. We aimed...

Repositório Covid-19
01/04/2022

Implementation of corticosteroids in treatment of COVID-19 in the ISARIC WHO Clinical Characterisation Protocol UK: prospective, cohort study

Dexamethasone was the first intervention proven to reduce mortality in patients with COVID-19 being treated in hospital. We aimed to...

Repositório Covid-19
31/03/2022

Effectiveness of CoronaVac, ChAdOx1 nCoV-19, BNT162b2, and Ad26.COV2.S among individuals with previous SARS-CoV-2 infection in Brazil: a test-negative, case-control study

COVID-19 vaccines have proven highly effective among individuals without a previous SARS-CoV-2 infection, but their effectiveness in preventing symptomatic infection...

Repositório Covid-19
31/03/2022

Telomere-length dependent T-cell clonal expansion: A model linking ageing to COVID-19 T-cell lymphopenia and mortality

Severe COVID-19 T-cell lymphopenia is more common among older adults and entails poor prognosis. Offsetting the decline in T-cell count...

Repositório Covid-19
Os impactos da guerra sobre a indústria farmoquímica
30/03/2022

Os impactos da guerra sobre a indústria farmoquímica

Diante da guerra da Rússia X Ucrânia, a indústria farmoquímica enfrenta incertezas, além das consequências da pandemia de Covid-19. Todo...

Associado em foco
30/03/2022

Effect of Early Treatment with Ivermectin among Patients with Covid-19

The efficacy of ivermectin in preventing hospitalization or extended observation in an emergency setting among outpatients with acutely symptomatic coronavirus...

Repositório Covid-19
30/03/2022

Early Outpatient Treatment for Covid-19 with Convalescent Plasma

Polyclonal convalescent plasma may be obtained from donors who have recovered from coronavirus disease 2019 (Covid-19). The efficacy of this...

Repositório Covid-19
30/03/2022

BNT162b2 Protection against the Omicron Variant in Children and Adolescents

Spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.1.529 (omicron) variant, which led to increased U.S. hospitalizations for...

Repositório Covid-19
29/03/2022

Veja a lista de emagrecedores irregulares publicada pela Anvisa

A Agência Nacional de Vigilância Sanitária (Anvisa) divulgou em seu site uma lista de emagrecedores irregulares que estão proibidos de serem...

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