Notícias17/08/2022 Monoclonal antibodies: a remedial approach to prevent SARS-CoV-2 infectionAbstractSARS-CoV-2, the newly emerged virus of the Coronaviridae family is causing havoc worldwide. The novel coronavirus 2019 was first... Repositório Covid-1916/08/2022 Clinical Practice Guidelines From the Association for the Advancement of Blood and Biotherapies (AABB): COVID-19 Convalescent PlasmaAbstractDescription:Coronavirus disease 2019 convalescent plasma (CCP) has emerged as a potential treatment of COVID-19. However, meta-analysis data and... Repositório Covid-1915/08/2022 Chamada Pública Nº 13/2022 – Prorrogação de prazoO Instituto de Tecnologia em Fármacos – Farmanguinhos/Fiocruz, tendo em vista a previsão do item 4.3 da Chamada Pública nº... Associado em foco15/08/2022 Chamada Pública Nº 12/2022 – Prorrogação de prazoO Instituto de Tecnologia em Fármacos – Farmanguinhos/Fiocruz, tendo em vista a previsão do item 4.3 da Chamada Pública nº... Associado em foco12/08/2022 Evaluation of safety and immunogenicity of receptor-binding domain-based COVID-19 vaccine (Corbevax) to select the optimum formulation in open-label, multicentre, and randomised phase-1/2 and phase-2 clinical trialsSummaryBackgroundWe assessed the efficacy of a receptor-binding domain (RBD)-based protein subunit COVID-19 vaccine. Repositório Covid-1912/08/2022 Structure-Based Identification of Naphthoquinones and Derivatives as Novel Inhibitors of Main Protease Mpro and Papain-like Protease PLpro of SARS-CoV-2AbstractThe worldwide COVID-19 pandemic caused by the coronavirus SARS-CoV-2 urgently demands novel direct antiviral treatments. The main protease (Mpro)... Repositório Covid-1912/08/2022 PIKfyve-specific inhibitors restrict replication of multiple coronaviruses in vitro but not in a murine model of COVID-19AbstractThe ongoing COVID-19 pandemic has claimed more than 6 million lives and continues to test the world economy and... Repositório Covid-1912/08/2022 Mesenchymal stem cells and their derived small extracellular vesicles for COVID-19 treatmentAbstractSince December 2019, the coronavirus (COVID-19) pandemic has imposed huge burdens to the whole world, seriously affecting global economic... Repositório Covid-1912/08/2022 Interleukin-6 cytokine: An overview of the immune regulation, immune dysregulation, and therapeutic approachAbstractSeveral studies have shown that interleukin 6 (IL-6) is a multifunctional cytokine with both pro-inflammatory and anti-inflammatory activity, depending... Repositório Covid-1911/08/2022 Safety of COVID-19 vaccines in pregnancy: a Canadian National Vaccine Safety (CANVAS) network cohort studySummaryBackgroundPregnant individuals have been receiving COVID-19 vaccines following pre-authorisation clinical trials in non-pregnant people. This study aimed to... Repositório Covid-1911/08/2022 Effectiveness of BNT162b2 Vaccine against Omicron in Children 5 to 11 Years of AgeAbstractBACKGROUNDSince it was first identified in early November 2021, the B.1.1.529 (omicron) variant of severe acute respiratory syndrome... Repositório Covid-1911/08/2022 Bio-Manguinhos/Fiocruz inicia o fornecimento de adalimumabe biossimilar ao Sistema Único de SaúdeFruto de uma Parceria para o Desenvolvimento Produtivo (PDP), o medicamento adalimumabe começa a ser fornecido ao Sistema Único de... Associado em foco
17/08/2022 Monoclonal antibodies: a remedial approach to prevent SARS-CoV-2 infectionAbstractSARS-CoV-2, the newly emerged virus of the Coronaviridae family is causing havoc worldwide. The novel coronavirus 2019 was first... Repositório Covid-19
16/08/2022 Clinical Practice Guidelines From the Association for the Advancement of Blood and Biotherapies (AABB): COVID-19 Convalescent PlasmaAbstractDescription:Coronavirus disease 2019 convalescent plasma (CCP) has emerged as a potential treatment of COVID-19. However, meta-analysis data and... Repositório Covid-19
15/08/2022 Chamada Pública Nº 13/2022 – Prorrogação de prazoO Instituto de Tecnologia em Fármacos – Farmanguinhos/Fiocruz, tendo em vista a previsão do item 4.3 da Chamada Pública nº... Associado em foco
15/08/2022 Chamada Pública Nº 12/2022 – Prorrogação de prazoO Instituto de Tecnologia em Fármacos – Farmanguinhos/Fiocruz, tendo em vista a previsão do item 4.3 da Chamada Pública nº... Associado em foco
12/08/2022 Evaluation of safety and immunogenicity of receptor-binding domain-based COVID-19 vaccine (Corbevax) to select the optimum formulation in open-label, multicentre, and randomised phase-1/2 and phase-2 clinical trialsSummaryBackgroundWe assessed the efficacy of a receptor-binding domain (RBD)-based protein subunit COVID-19 vaccine. Repositório Covid-19
12/08/2022 Structure-Based Identification of Naphthoquinones and Derivatives as Novel Inhibitors of Main Protease Mpro and Papain-like Protease PLpro of SARS-CoV-2AbstractThe worldwide COVID-19 pandemic caused by the coronavirus SARS-CoV-2 urgently demands novel direct antiviral treatments. The main protease (Mpro)... Repositório Covid-19
12/08/2022 PIKfyve-specific inhibitors restrict replication of multiple coronaviruses in vitro but not in a murine model of COVID-19AbstractThe ongoing COVID-19 pandemic has claimed more than 6 million lives and continues to test the world economy and... Repositório Covid-19
12/08/2022 Mesenchymal stem cells and their derived small extracellular vesicles for COVID-19 treatmentAbstractSince December 2019, the coronavirus (COVID-19) pandemic has imposed huge burdens to the whole world, seriously affecting global economic... Repositório Covid-19
12/08/2022 Interleukin-6 cytokine: An overview of the immune regulation, immune dysregulation, and therapeutic approachAbstractSeveral studies have shown that interleukin 6 (IL-6) is a multifunctional cytokine with both pro-inflammatory and anti-inflammatory activity, depending... Repositório Covid-19
11/08/2022 Safety of COVID-19 vaccines in pregnancy: a Canadian National Vaccine Safety (CANVAS) network cohort studySummaryBackgroundPregnant individuals have been receiving COVID-19 vaccines following pre-authorisation clinical trials in non-pregnant people. This study aimed to... Repositório Covid-19
11/08/2022 Effectiveness of BNT162b2 Vaccine against Omicron in Children 5 to 11 Years of AgeAbstractBACKGROUNDSince it was first identified in early November 2021, the B.1.1.529 (omicron) variant of severe acute respiratory syndrome... Repositório Covid-19
11/08/2022 Bio-Manguinhos/Fiocruz inicia o fornecimento de adalimumabe biossimilar ao Sistema Único de SaúdeFruto de uma Parceria para o Desenvolvimento Produtivo (PDP), o medicamento adalimumabe começa a ser fornecido ao Sistema Único de... Associado em foco