Repositório Covid-19

The emergence of SARS-CoV-2 variants of concern suggests viral adaptation to enhance human-to-human transmission1,2. Although much effort has focused on...

Remdesivir improves clinical outcomes in patients hospitalized with moderate-to-severe coronavirus disease 2019 (Covid-19). Whether the use of remdesivir in symptomatic,...

The coronavirus disease 2019 (COVID-19) pandemic caused by the coronavirus—severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to cause global...

As the latest identified novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant of concern (VOC), the influence of Omicron...

Macrodomains are a class of conserved ADP-ribosylhydrolases expressed by viruses of pandemic concern, including coronaviruses and alphaviruses. Viral macrodomains are...

The Coronavirus disease 2019 (COVID-19) pandemic is one of the most devastating global problems. Regarding the lack of disease-specific treatments,...

Treatments for coronavirus disease 2019, which iscaused by severe acute respiratory syndrome coronavirus-2(SARS-CoV-2), are urgently needed but remain limited. SARSCoV-2...

Given the emergence of the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), which particularly threatens older people with comorbidities such as diabetes...

Since the first cases of COVID-19 were documented in Wuhan, China in 2019, the world has witnessed a devastating global...

COVID-19 is characterized by vascular inflammation and thrombosis, including elevations in P-selectin, a mediator of inflammation released by endothelial cells....

After promising initial results from the administration of a third (booster) dose of the BNT162b2 messenger RNA vaccine (Pfizer–BioNTech) to...