Based on the results of some large randomized controlled trials (RCTs) confirmed the efficacy of corticosteroids in coronavirus disease 2019 (COVID-19), corticosteroids have been included in World Health Organization guidelines, but remain controversial.

Lin L, Xue D, Chen JH, Wei QY, Huang ZH. Methylprednisolone accelerate chest computed tomography absorption in COVID-19: A three-centered retrospective case control study from China. World J Clin Cases 2022; 10(2): 426-436 [PMID: 35097067 DOI: 10.12998/wjcc.v10.i2.426]

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Angiotensin II infusion in COVID-19: An international, multicenter, registry-based study

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ACE2 Shedding and the Role in COVID-19