The new Coronavirus (SARS-CoV-2) created a pandemic in the world in late 2019 and early 2020. Unfortunately, despite the increasing prevalence of the disease, there is no effective drug for the treatment. A computational drug repurposing study would be an appropriate and rapid way to provide an effective drug in the treatment of the coronavirus disease of 2019 (COVID-19) pandemic. In this study, the inhibitory potential of more than 50 antiviral drugs on three important proteins of SARS-CoV-2, was investigated using the molecular docking method.

Matéria original

Anterior

Tofacitinib in Patients Hospitalized with Covid-19 Pneumonia

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Dynamic Profiling of β-Coronavirus 3CL Mpro Protease Ligand-Binding Sites